Contact/Scientist: Dr. Stephen Ferguson
Professor, Department of Cellular and Molecular Medicine | Tier 1 Canada Research Chair uOBMRI
A full-time research technician position is immediately available In the Ferguson laboratory at Roger in the Department of Cellular and Molecular Medicine, Roger Guindon Hall at the University of Ottawa.
Dr. Ferguson’s laboratory is interested in the regulation of G protein-coupled receptor (GPCR) signaling. The laboratory studies the molecular mechanisms underlying the signaling, endocytosis and recycling of GPCRs and how this regulates the cell biology of GPCR function in cell culture as well as animal models of disease. The focus of the laboratory is on Alzheimer’s and Huntington’s disease, stress and anxiety and hypertension and involves the study of glutamate, CRF and angiotensin receptors.
The position will involve: extensive experience with molecular biological techniques, site directed mutagenesis, siRNA, and CRISPR/Cas9. The successful applicant should also have extensive skill in protein biochemistry including but not limited to: SDS PAGE, immunoblot, immunohistochemistry, BRET, FRET and ELISA. The position will also involve maintenance of immortal and primary cell lines and the preparation of neuronal cultures from timed pregnant mice as well as lab management, ordering and data analysis and record keeping. The successful candidate will be expected to work in coordination with the PI to facilitate the research and graduate students and postdoctoral fellows in the laboratory. The candidate requires a strong work ethic and enthusiasm to work independently while being part of a research team.
- Knowledge of basic science and biological sciences
- Extensive molecular biology expertise
- Extensive protein chemistry expertise
- Experience with the preparation of primary neuronal cultures and tissue collection
- High proficiency computer skills
- Ability to balance multiple priorities
- Preferably a M.Sc. degree or a minimum of a Bachelor degree and two years related experience, or relevant experience in lieu of education.
- Excellent oral and written communication skills in English
This position is a 12-month contract.
Salary: A competitive package of salary and benefits will be offered to the successful candidate based on qualifications and experience.
Please send resume, a brief statement of research experience and career goals, and telephone number and email addresses of three (3) references to Dr. Stephen Ferguson: firstname.lastname@example.org
Contact/Scientist: Dr. Damien D’Amours
Professor | Department of Cellular and Molecular Medicine
Dr. D’Amours is currently looking for a Research Associate (2) to work on a full-time basis (37.5 hours per week). The Research Associate will work independently at a senior level to evaluate data and prepare technical reports, including recommendations based upon findings. In addition, the Research Associate will provide technical assistance to students and academic staff.
The central research focus of the D’Amours laboratory is the biochemical, structural and genetic analysis of protein complexes involved in the maintenance of genome architecture and DNA repair (for a recent example, see Thattikota et al., Molecular Cell, 2018).
Dr. D'Amours is looking for someone with a Ph.D. (preferred) or a minimum of Master’s degree in the area of protein biochemistry plus 3-5 years of relevant experience. Extensive expertise in protein purification and structural analysis will be considered an asset.
Please click here for more information or to apply.
The Faculty of Medicine at the University of Ottawa, in collaboration with the Regenerative Medicine Program of the Ottawa Hospital Research Institute, invites applications for a tenure-track position in regenerative medicine. Click here for more information.