Walker, Mark

Dr, Mark Walker

Dr. Mark Walker MD, FRCSC, MSc, MHCM
Chair and Professor, University of Ottawa

Chief
Dept. Obstetrics, Gynecology & Newborn Care, Div Maternal-Fetal Medicine

The Ottawa Hospital

Senior Scientist,
Ottawa Hospital Research Institute Clinical Epidemiology

Contact Information

The Ottawa Hospital, General Campus
501 Smyth Rd, Box 804
Ottawa, ON K1H 8L6
Phone: 613-737-8877 x71246
Fax: 613-737-8070
Email: mwalker@ottawahospital.on.ca

Biography

Health services research, population health research, and clinical studies in perinatology

Dr. Walker earned his Medical Degree from Queens University, Kingston, Ontario (1993).  His Residency Training in Obstetrics and Gynecology was completed at the University of Ottawa, Ontario (1998); followed by a Fellowship in Maternal-Fetal Medicine at the University of Toronto. Dr. Mark Walker is a high risk obstetrician and Clinical Epidemiologist at the University of Ottawa.  He has published over 160 peer reviewed articles and has made a significant impact in our understanding of folic acid in pregnancy, thrombophilia in pregnancy, and is a highly regarded perinatal health services researcher.

Dr. Walker’s leadership roles include the Chair of the Society of Investigators in Obstetrics and Gynecology, the co-Chair of the Provincial Council for Maternal Newborn Health, the scientific Director and co-director of BORN (Better Outcomes Registry and Network) and the co-chair of the Canadian Perinatal Surveillance System’s Maternal Infant Study Group.  He currently holds a Tier 1 Chair from the University of Ottawa in Perinatal Research.  He is co-founder of the OMNI Research Group (Obstetrics, Maternal and Newborn Investigations) at the Ottawa Hospital which is the largest maternal and newborn research group in Canada and ranks in the top 5 in the world. 

Research

Health services research, population health research, and clinical studies in perinatology

Dr. Mark Walker is a Perinatologist and Clinical Epidemiologist.  In 2000, he teamed up with Dr. Shi Wu Wen, a perinatal epidemiologist and together they founded the OMNI (Obstetrics & Maternal Newborn Investigations) Research Group.  This is a group of investigators who are committed to the betterment of health for pregnant women and their infants.  The main areas of research focus are fetal origins of adult diseases, perinatal environmental epidemiology and global health.  Maternal-fetal research is now one of the main themes of investigation within the Clinical Epidemiology Program.  Dr. Walker has been successful in attaining funds from the Canada Foundation for Innovation (CFI), Canadian Institutes of Health Research (CIHR), Physicians’ Services Incorporated (PSI) and the Heart and Stroke Foundation (HSF).  Currently, he and Dr. Wen are part of a new emerging team from the CIHR on pre-eclampsia.

The OMNI Research Group is currently composed of 3 Principal Investigators (Drs. Mark Walker, Shi Wu Wen and Qiuying Yang); 1 Research Manager (Ruth Rennicks White)  2 Research Administrative Assistants (Diane Gorley and Jody Peters); 1 Administrative Assistant (Wen Liang Zeng); 6 Postdoctoral Research Fellows (Drs. Xi Kuan Chen, Jun Gao, Tubao Yang, Aizhong Liu , Juan Vazquez and Chayawat Phatihattakorn and 6 Research Nurses/Coordinators (Melanie Good, Pauline Shields, Maureen Rybak,  Lucy Chura, Svetlana Shachkina and Shannon Edwards).

One of the hallmark studies Dr. Walker has been involved in along with Dr. Wen and Dr. Marc Rodger, is the Ottawa Birth Cohort.  This is an inception cohort for which subjects are recruited during gestation between the 12th and 20th week of pregnancy.  The pregnancies are then followed to term.  Data on DNA, environmental contaminants as well as epidemiologic and biochemical information is collected.  These variables will then be studied to determine the causes of adverse pregnancy outcomes such as stillbirth, intra-uterine growth restriction, pre-eclampsia and placental abruption.  Our goal is then to turn this pregnancy cohort into a birth cohort in which infants will be followed in perpetuity.

Dr. Walker is currently the Program Director for the Maternal-Fetal Medicine Clinical Fellowship Education Program. He has supervised 22 Clinical Fellows and 9 Residents in his capacity as both Program Director and active staff member.  Four of the Fellows/Residents have won peer reviewed grants to perform their research and five have won research awards at both the local and national levels.  He has also supervised 8 International Postdoctoral Research Fellows, four Graduate and twelve Undergraduate students.

See “highlights” of his career below.

Publications

Published – Peer Reviewed

86

 

Published – Non Peer Reviewed

1

 

In Press

10

 

Submitted

9

Book Chapters

Published

1

Abstracts

 

91

Presentations

 

39

Awards

Research

21

 

Teaching

6

Scholarly Activities

 

26

Research Funding

Current

19

 

Fellowships/Bursaries

2

 

Completed

36

 

Pending

3

Supervision

Post-doctoral - Research

9

 

Fellows/Residents - Clinical

22

 

Graduate Students

4

 

Undergraduate Students

16

Publications Published – past two years:

  • Donald T. Wigle, Tye E. Arbuckle, Mark Walker, Michael G. Wade, Shiliang Liu, Daniel Krewski.  Environmental hazards:  Evidence for effects on child health.  Journal of Toxiology and environmental Health, Part B, 2007, 10:3-39.
  • Graeme N. Smith, Mark Walker, et al.  Randomized double-blind placebo-controlled trial of transdermal nitroglycerin for preterm labor.  American Journal of Obstetrics and Gynecology.  Jan 2007, 196(1): 37-38
  • Xi-Kuan Chen, Graeme Smith, Mark Walker.  Pregnancy induced hypertension and infant mortality:  roles of birthweight centiles and gestational age.  British Journal of Obstetrics and Gynecology. 2007, 114(1): 24-31
  • Xi-Kuan Chen, Shi Wu Wen, Graeme Smith, Qiuying Yang, Mark Walker.  New onset hypertension in late pregnancy is associated with lower fetal and infant mortality in preterm twins.  Hypertension in Pregnancy.  2006, 25; 205-216
  • Xi-Kuan Chen, Shi Wu Wen, Graeme Smith, Art Leader, Marilyn Sutandar, Qiuying Yang, Mark Walker.  Maternal age, paternal age and new onset hypertension in late pregnancy.  Hypertension in Pregnancy.  2006, 25: 217-227
  • Peter CW Kim, Mark Walker, Mary-Agnes Beduz for the Fetal Alert Network.  The Fetal Alert Network:  An innovative Program of Access to Care, Surveillance, and Education for Birth Defects in Ontario.  Journal of Obstetrics and Gynecology of Canada, 2006 December, 28(12); 1099-1102
  • Edris F, Walker M, Wen SW, Yang Q.  The relationship between inter-twin delivery interval and metabolic acidosis in the second twin.  American Journal of Perinatology.  Nov 2006, 23(8): 481-485
  • SD McDonald, M Walker, SL Perkins, J Beyene, K Murphy, W Gibb, A Ohlsson.  The effect of tobacco exposure on the fetal hypothalamic-pituitary-adrenal axis.  British Journal of Obstetrics and Gynecology.  2006, 113: 1289-1295
  • Wen SW, Tan H, Walker M.  The association between intratwin birthweight discordance and preterm birth in twin pregnancy.  Australian New Zealand Journal of Obstetrics and Gynecology.  2006 Oct; 46(5): 402-406
  • Jennifer E Soucie, Qiuying Yang, Shi Wu Wen, Karen Fung Kee Fung,Mark Walker.  Neonatal mortality & morbidity in term twins with advancing gestational age.  American Journal of Obstetrics and Gynecology,  2006, July: 195(1); 172-177
  • Tan H, Wen SW, Chen XK, Demissie K, Walker M.  Early prediction of preterm birth for singleton, twin, and triplet pregnancies.  European Journal of Obstetrics and Gynecology Reproductive Biology.  2006 June 10; Epub ahead of print
  • Wen SW, Tan H, Yang Q, Walker M.  Prediction of intra-twin birth weight discordance by binary logistic regression analysis.  Gynecological and Obstetrical Investigations.  2006 June 15; 62(4): 186-192
  • Wen SW, Tan H, Yang Q, Walker M.  Prediction of intra-twin birth weight discordance by binary logistic regression analysis.  Gynecology and Obstetrical Investigations 2006, June 15;62(4): 186-192
  • Qiuying Yang, Shi Wu Wen, Graeme N. Smith, Yue Chen, Daniel Krewski, Xi Kuan Chen, Mark C. Walker.  Maternal cigarette smoking and the risk of pregnancy-induced hypertension and eclampsia.  International Journal of Epidemiology.  2006, April: 35(2); 288-293
  • Xi-Kuan Chen, Shi Wu Wen, Graeme Smith, Qiuying Yang, Mark Walker.  Pregnancy-induced hypertension is associated with lower infant mortality in preterm singletons.  British Journal of Obstetrics and Gyneacology.  May 2006, 113(5): 544-551
  • Roberta Mackenzie, Mark Walker, Anthony Armson, Mary E. Hannah.  Progesterone for the prevention of preterm birth among women at increased risk:  a systematic review and meta-analysis of randomized controlled trials.  American Journal of Obstetrics and Gynecology. May 2006, 194; 1234-1242
  • Xi Kuan Chen, Shi Wu Wen, Qiuying Yang, Daniel Krewski, Graeme Smith, Mark Walker.  Environmental lead exposure and pregnancy-induced hypertension.  Environmental Research.  2006 March 100(3); 424-430
  • Shi Wu Wen, Qiuying Yang, Peter Garner, William Fraser, Olufemi Olatunbosun, Carl Nimrod, Mark Walker.  Selective serotonin reuptake inhibitors and adverse pregnancy outcomes.  American Journal of Obstetrics and Gynecology (2006) 194: 961-966
  • Marc A Rodger, Leonard I Avruch, Heather E Howley, Andre Olivier,Mark C Walker.  Pelvic magnetic resonance venography reveals high rate of pelvic vein thrombosis following cesarean section.  American Journal of Obstetrics and Gynecology 2006.194: 436-437
  • Yang Q, Wen SW, Chen Y, Krewski D, Fung KF, Walker M.  Neonatal mortality and morbidity in vertex-vertex second twins according to mode of delivery and birth weight.  American Journal of Perinatology 2006, Jan; 26(1): 3-10
  • Wen SW, Tan H, Yang Q, Walker M.  Prediction of small for gestational age by logistic regression in twins.  Australian New Zealand Journal of Obstetrics and Gynecology 2005 Oct; 45(5): 399-404
  • Mark Walker, Qiuying Yang.  Paternal influences on birth defects: Maybe older men should reflect before becoming Dads.  Parkhurst Exchange, November 2005, page 19
  • Fawaz Edris, Ania Kielar, Karen Fung Kee Fung, Leonard Avruch,Mark Walker.  Ultrasound and MRI in the antenatal diagnosis of schizencephaly. Journal of Obstetrics and Gynecology, Sept 2005; 27(9): 864-868
  • H Tan, SW Wen, K Fung Kee Fung, M Walker, K Demissie.  The distribution of intra-twin birth weight discordance and its association with total twin birth weight, gestational age, and neonatal mortality.  European Journal of Obstetrics, Gynecology and Reproductive Biology 2005; 121: 27-33
  • Graeme N. Smith, Christine Rafuse, Nitasha Anand, Barb Brennan, Greg Connors, Joan Crane, William Fraser, Robert Gratton, Jean-Marie Moutquin, Heather Scott, Carole Schneider, Mark Walker.  Prevalence, management, and outcomes of preterm prelabour rupture of the membranes of women in Canada.  Journal of Obstetrics and Gynecology of Canada, June 2005; 27(6): 547-553
  • McDonald SD, Perkins SL, Walker M.  Correlation between self-reported smoking status and serum cotinine during pregnancy.  Addictive Behaviors.  2005 30/4: 853-857
  • Howley Heather HA, Rodger M, Walker M.  A systematic review of the association between Factor V Leiden (FVL) or prothrombin gene variant (PGV) and intrauterine growth restriction (IUGR).  American Journal of Obstetrics and Gynecology.  2005.  192: 694-708
  • Tan H, Wen SW, Gagnon F, Walker M.  The estimation of heritability for twin data based on concordance of sex and disease.  Chronic Diseases in Canada.  Winter 2005, 26(1): 9-12
  • Tam LE, McDonald SD, Wen SW, Smith GN, Windrim RC, Walker MC.  A survey of preconceptional folic acid use in a group of Canadian women.  Journal of Obstetrics and Gynecology of Canada, March 2005.  27(3), 232-236
  • Qiuying Yang, Shi Wu Wen, Ye Chen, Daniel Krewski, Karen Fung Kee Fung, Mark Walker.  Neonatal death and morbidity in vertex-nonvertex second twins according to mode of delivery and birth weight.  American Journal of Obstetrics and Gynecology. 2005 192: 840-847
  • Qiuying Yang, Shi Wu Wen, Ye Chen, Daniel Krewski, Karen Fung Kee Fung, Mark Walker.  Occurrence and clinical predictors of operative delivery for the vertex second twin after normal vaginal delivery of the first twin.  American Journal of Obstetrics and Gynecology.  2005 192: 178-184
  • Shi Wu Wen, Mark Walker.  An exploration of health effects of folic acid in pregnancy beyond reducing neural tube defects.  Journal of Obstetrics and Gynecology of Canada.  2005 27(1); 13-19

Abstracts – past two years:

  • Darine El-Chaar, Mark Walker, et al.  Risk of birth defects in pregnancies associated with assisted reproductive technology (ART).  Society for Maternal-Fetal Medicine 27th Annual Meeting, San Francisco, CA, February 5-10, 2007
  • Sarah D. McDonald, Mark Walker, Joseph Beyene, Kellie Murphy, Graeme Smith, Sherry L. Perkins, Arne Ohlsson. The effect of tobacco exposure on maternal and fetal thyroid function.  Society for Maternal-Fetal Medicine 27th Annual Meeting, San Francisco, CA, February 5-10, 2007
  • Darine El-Chaar, Mark Walker, et al.  Risk of birth defects in pregnancies associated with assisted reproductive technology (ART).  Kingston, ON, November 2-3, 2006
  • Migahed L, Gao J, Yang Q, Bottomly J, Wen SW, Walker M.  Trends in cesarean deliveries in low-risk nulliparous women in Ontario.  Canadian Perinatal Health Services Research:  Towards a national database, Kingston, ON, November 2-3, 2006
  • Karel O’Brien, Arne Ohlsson, Rory Windrim, Mark Walker, Graeme Smith.  Transdermal nitroglycerin for preterm labor.  2006 Pediatric Academic Societys’ Annual Meeting, San Francisco, USA, April 30, 2006
  • Fawaz Edris, Lawrence Oppenheimer, Qiuying Yang, Shi Wu Wen, Karen Fung Kee Fung, Mark Walker.  The relationship between inter-twin delivery interval and metabolic acidosis in the second twin.  26th Society of Maternal Fetal Medicine Annual Meeting, Miami, Florida, January 29-February 4, 2006
  • KP Phillips, MC Walker, M Weselak.  Geographic variation in semen quality: Meta-analysis of semen quality literature.  University of Ottawa Applied Health & Social Research Network’s 3rd Annual Symposium, Fostering Research Connections, December 6, 2005
  • M Walker, J Lougheed, W Gibb, M Lawson, C Nimrod, R Walker, S Perkins, SW Wen, S Chen.  Repeated courses of antenatal steroids and cardiovascular and endocrine function in children ages 6 to 11.  First Sino-Canada Bilateral Workshop on Reproductive Health Research, Beijing, China, November 15-18, 2005
  • X-K Chen, SW. Wen, GN Smith, Q Yang, M Walker.  Pregnancy-induced hypertension is associated with lower infant mortality in preterm singletons.  29th Annual Perinatal Investigators Meeting, Kingston, November 4, 2005
  • Shi Wu Wen, Qiuying Yang, Peter Garner (deceased), William Fraser, Olufemi Olatunbosun, Carl Nimrod, Mark Walker.  Selective serotonin reuptake inhibitors (SSRIs) and adverse pregnancy outcomes.  Faculty Research Day, University of Ottawa, October 19, 2005
  • Qiuying Yang, Mark C. Walker, Xi-Kuan Chen, Daniel Krewski, Karen Fung Kee Fung, Shi Wu Wen.  Impacts of operative delivery for the first twin on neonatal outcomes in the second twin.  Faculty Research Day, University of Ottawa, October 19, 2005
  • E Jolly, K Fung Kee Fung, P Rasuli, S Goulet, S Lago, M Walker.  Long term follow up of ovarian volume after uterine artery embolization.  15th World Congress on Ultrasound in Obstetrics and Gynecology, September 25-29, 2005, Vancouver
  • Karen Phillips, Mark Walker, Mandy Weselak.  Geographic variation in semen quality: Meta-analysis of semen quality literature.  38th Annual Meeting, Society for the Study of Reproduction, Quebec, July 24-27, 2005, Biology of Reproduction-Special Issue, p133
  • M Walker, X Chen, M Sutandar, Q Yang, S Wen.  Impacts of inadequate prenatal care on neonatal mortality in high-risk women.  Society of Obstetricians and Gynecologists of Canada 61st Annual Clinical Meeting, Quebec, June 16-21, 2005; JOGC Supplement, Vol 27(5), S17
  • M Walker, J Lougheed, W Gibb, M Lawson, C Nimrod, R Walker, S Perkins, S Wen, X Chen.  Repeated courses of antenatal steroids and cardiovascular and endocrine function in children ages 6 to 11.  Society of Obstetricians and Gynecologists of Canada 61st Annual Clinical Meeting, Quebec, June 16-21, 2005; JOGC Supplement, Vol 27(5), S23 (BEST ORAL Presentation)
  • M Walker, Q Yang, S Wen, J Soucie, K Fung Kee Fung.  Neonatal mortality in term twins with advancing gestational age.  Society of Obstetricians and Gynecologists of Canada 61st Annual Clinical Meeting, Quebec, June 16-21, 2005; JOGC Supplement, Vol 27(5), S25
  • M Walker, Q Yang, S Wen, X Chen, J Lipson, A Leader.  Paternal age and risk of birth defects in singleton gestations.  Society of Obstetricians and Gynecologists of Canada 61st Annual Clinical Meeting, Quebec, June 16-21, 2005; JOGC Supplement, Vol 27(5),S27
  • M Walker, S Wen, H Tan, X Chen.  Prediction of early preterm in singleton, twin and triplet pregnancies.  Society of Obstetricians and Gynecologists of Canada 61st Annual Clinical Meeting, Quebec, June 16-21, 2005; JOGC Supplement, Vol 27(5), S35
  • Natasha O’Reilly, Beth Potter, Isabelle Boland, Yelena Chorny, Ian Graham, Mario Cappelli, Doug Coyle, Mark Walker, Brenda Wilson.  Women’s Perspectives on Genetics:  Understanding, Expectations, and Values.  3rd International Shared Decision Making Conference: Implementing Shared Decision Making in Diverse Health Care Systems and Cultures, Ottawa, June 14-16, 2005
  • Yang Q, Wen SW, Chen Y, Krewski D, Fung Kee Fung K, Walker M.  Neonatal mortality and morbidity in vertex-nonvertex second twins according to mode of delivery and birth weight.  Society of Maternal-Fetal Medicine 25th Annual Meeting, Reno, Nevada, February 7-12, 2005
  • Clement A.M on behalf of the TIPPS Investigators.  Prevalence of Factor V Leiden and Prothrombin mutation in women with a history of placenta mediated pregnancy complications.  Society of Maternal-Fetal Medicine 25th Annual Meeting, Reno, Nevada, February 7-12, 2005
  • Ouellet A, Gruslin A, Walker M.  Prospective ultrasound measurements of the placenta using panoramic view.  Society of Maternal-Fetal Medicine 25th Annual Meeting, Reno, Nevada, February 7-12, 2005
  • Q Yang, SW Wen, GN Smith, Y Chen, D Krewski, X-K Chen, MC Walker.  Maternal cigarette smoking decreases the risk of pregnancy-induced hypertension and eclampsia in an exposure-response relationship.  American Journal of Epidemiology 2005; 161 (Suppl): S114
  • X-K Chen, SW Wen, Q Yang, MC Walker.  Impacts of inadequate prenatal care on infant mortality in high-risk women.  American Journal of Epidemiology 2005, 161 (Suppl) S110
  • Q Yang, SW Wen, J Soucie, K Fung kee Fung, MC Walker.  Neonatal mortality in term twins with advancing gestational age.  American Journal of Epidemiology 2005; 161 (Suppl) S94

Presentations – past two years:

  • Pre-eclampsia – Emerging therapies, Society for Maternal-Fetal Medicine, 27th Annual Meeting, San Francisco, CA, February 5-10, 2007
  • Maternal and Child Health Drug Safety.  University of Ottawa, Pharmacovigilance Workshop, Ottawa, January 26, 2007
  • TIPPS:  Thrombophilia in pregnancy prophylaxis study.  Grand Rounds, McGill University, Montreal, January 19, 2007
  • Canadian Perinatal Health Services Research:  Towards a national database.  Workshop Organizer, Kingston, November 2-3, 2006
  • Medical Complications in Pregnancy, Fetal Alert Network/Ontario’s Telehealth Network Education Series, Teleconference, Ottawa, October 26, 2006
  • Antenatal Screening.  Fetal Alert Network/Ontario’s Telehealth Network Education Series, Teleconference, Ottawa, November 24, 2005
  • Repeated courses of antenatal steroids and cardiovascular and endocrine function in children ages 6 to 11.  First Sino-Canada Bilateral Workshop on Reproductive Health Research, Beijing, China, November 15-18, 2005
  • Environmental and Fetal Origin of Disease, Endocrine Toxicants: Ecological and Population Health Impact Workshop, University of Ottawa, Ottawa, October 28, 2005
  • Fetal Development – Life’s Greatest Miracle.  Mini-Medical School, University of Ottawa, October 20, 2005
  • The Ottawa Birth Cohort.  Birth Cohorts & Determinants of Childhood Obesity, China-Canada Workshop, October 11, 2005, Ottawa
  • Integrating Evidence and Practice:  The Way Forward.  Society of Obstetricians and Gynecologists of Canada 61st Annual Clinical Meeting, June 16-21, 2005, Quebec
  • The Ottawa Birth Cohort…The Mother of all Studies.  Ottawa Health Research Institute Scientist Retreat, April 14-15, 2005, Lac Carling, Quebec
  • Fetal development: Life’s greatest miracle.  Mini-Medical School, Faculty of Medicine, University of Ottawa, March 31, 2005

Scholarly and Professional Activities – current:

  • Committee Member, Canadian Institutes of Health Research, Clinical Investigation – A Grants Committee, July 2005 to present
  • Program Director, Post-Graduate Fellows Medical Education, Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, July 2005 to present
  • Member, Neonatal-Perinatal Medicine Program Committee, 2005 to present
  • Member, Niday Perinatal Database Committee, 2005 to present
  • Member, EORLA Genetics Discipline Specific Working Group on new regional lab initiative, Department of Genetics, Children’s Hospital of Eastern Ontario (CHEO), 2005 to present
  • Member, PPPESO (Perinatal Partnership Program of Eastern and Southeastern Ontario, 2004 to present
  • Chair, Society of Investigators of Ob-Gyn of Canada (SIOGC), Sept 2004 to present
  • Abstract Subcommittee, Society of Obstetricians and Gynecologists Canada, 2002 to present
  • Scientific Organizing Committee, Society of Obstetricians and Gynecologists of Canada, 2002 to present

Current Research Funding:

  • Rodger M, Walker M, Wells, P, et al.  TIPPS - Thrombophilia in Pregnancy prophylaxis study.  Canadian Institutes of Health Research, Co-Investigator, $2,349,795, 2007-2012
  • Yang Q, Wen SW, Walker M, Bradwejn J, Fergusson D.  Perinatal outcomes in pregnant women treated with antidepressants.  Canadian Institutes of Health Research, $71,564, 09/2007-08/2008
  • Wen SW, Walker M, Yang Q, Rodger M, Smith G, Perkins S.  Folic acid supplementation in early second trimester and the risk of pre-eclampsia.  Canadian Institutes of Health Research, $394,089, 09/2007-08/2010
  • Fraser W, Wood S, Walker M, von Dadelszen P, McCoshen J, Lye S, Leung P, Klein M. Heaman M, Grant A.  Strategic training initiative in research in the reproductive health sciences.  Canadian Institute for Health Research, Co-Investigator, $4,200,000, 2001-2007
  • Baltz, J, Chian R-C, Claman, P, Clarke H, Leader A, Walker M, Wen SW, et al (Group Grant).  Program on Oocyte Health.  Canadian Institute for Health Research, Co-Investigator. $2,781,266, 2003-2007
  • Smith G, Graham CH, Kisilevsky B, MacDonald S, Walker M, Wen SW.  New Emerging Team Grant:  (PE-NET) Pre-eclampsia:  Fetal & maternal outcomes and innovative Therapies.  Canadian Institute for Health Research, Co-Investigator.  $1,739,481, 2003-2008.
  • Rodger M, Walker M, Wells P, Nair R, Wen SW.  TIGRESS – Thrombophilia and intrauterine growth restriction study.  Canadian Institute of Health Research, Co-Principal Investigator, $1,036,544, 2003-2008
  • Wen SW, Walker M, Nimrod C.  The use of folic acid antagonists in pregnancy and the incidence of birth defects and adverse fetal and infant outcomes.  Canadian Institute for Health Research.  $140,290, 2004-2007
  • Wen SW, Walker M, Sigal RJ, Nair R, Mbikay M.  Fetal macrosomia and adolescent obesity (CHOB).  Canadian Diabetes Association, $149,072, 2004-2007
  • Wells P, Rodger M, Gagnon F, Walker M.  Venous thrombosis: from bench to bedside to health economic and policy (QUEST).  Heart and Stroke Foundation, $1,250,000, 2004-2009
  • Wen SW, Walker M, Krewski D, Yang Q, Smith G.  Environmental carbon monoxide (CO) level and the risk of pre-eclampsia (PE).  Heart and Stroke Foundation, $56,839 2005-2007
  • Rodger M, Walker M (Co-PI), Keating S, Yang Q, Kingdom J, Wen SW, Smith G.  TAPP:  Thrombophilia and placental pathology, Heart and Stroke Foundation.  $123,849, 2005-2008
  • Walker M.  New Investigator Salary Support, Canadian Institutes of Health Research.  $275,000, July 2005-June 2010
  • Walker M (PI), Yang Q (Co-PI), Wen SW, Smith G, Little J, Bulman D.  Genomics and novel predictors of pre-eclampsia.  Physician Services Incorporated, March 2006-February 2008, $138,500
  • Fraser W, Julien P, Luo ZC, Shatenstein B, Audibert F, Walker M, et al. MIROS, Maternal-Infant Research on Oxidative Stress Study:  The effects and mechanisms of antioxidants for healthy pregnancy.  CIHR, 2005-2010, $1,612,194
  • Smith GN, Walker M.  Diagnosing the development of subclinical chorioamnionitis in women with preterm premature rupture of the membranes (PPROM), Physicians’ Services Incorporated, April 2006 – March 2008, $160,000.
  • Romano E, Kohen D, Walker M, Rodger M, Wen SW.  Prenatal factors and the impact on early child development:  Follow-up of a birth cohort study.  Canadian Institutes of Health Research, 2005-06, $100,000.
  • Phil Wells, France Gagnon, Susan Kahn, Mark Walker, Marc Rodger, Mike Kovacs.  Furthering Innovation in Thrombosis Research.  Canadian Institutes of Health Research, 04/2006 – 03/2011, $624,466
  • Magee LA, Liston R, Walker M, et al.  Birth under 29 weeks: Improving outcomes for mothers and babies.  Canadian Institutes of Health Research, 07/2005 -06/2009, $490,360

Research – Fellowships/Bursaries

  • Walker M, Wen SW, Gao J.  International Fellowship in China Collaboration in Perinatal Environmental Health, Post-graduate Medical Education, University of Ottawa, $40,000/year, 2005-2007
  • Chen X, Wen SW, Walker M (Co-Mentor).  Environmental carbon monoxide level and the risk of pre-eclampsia. STIRRHS Post-Graduate Fellowship, STIRRHS/CIHR. $74,000, July 2005-June 2007
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