Virus and targeted drug synergize to fight cancer in mice

Posted on Wednesday, August 26, 2020

While some cancer cells can be killed quickly by a single drug, the reality for patients is that multiple therapies are often required, especially if resistance develops.

A new study led by Dr. Jean-Simon Diallo reveals for the first time that two promising anti-cancer therapies can work together synergistically to kill cancer cells in laboratory and mouse models. The study is based on Dr. Diallo’s discovery several years ago that that compounds that disrupt a cell’s inner skeleton (called microtubule-destabilizing agents or MDAs) can enhance the ability of viruses to kill cancer cells.

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