Neda Nasheri

E-Card

Neda Nasheri
Adjunct Professor, Research Scientist, Health Canada

BSc, Baha’i Institute for Higher Education, Iran (2003)
MSc, University of Ottawa (2008)
PhD, University of Ottawa (2015)
NSERC Visiting Fellow, Health Canada (2015-2018)

Room: 251 Sir Frederick Banting Driveway, Rm E401

Work E-mail: neda.nasheri@canada.ca

Dr. Neda Nasheri

Biography

Research Interests

Dr. Nasheri’s research focuses on detection, characterization, and inactivation of foodborne viruses such as norovirus, hepatitis A virus, and hepatitis E virus. More recently, Dr. Nasheri’s team is working on examining potential risk for fecal-oral transmission of certain respiratory viruses such as human coronaviruses. Currently Dr. Nasheri is the head of the Food Virology Reference/Research at Health Canada.

The following are the highlights of her research activities:

  • Developing methods for the detection of foodborne viruses
  • Performing genomic characterization of foodborne viruses
  • Exploring novel inactivation methods and approaches
  • Tracing reservoirs for transmission of enteric viruses in foods
  • Food Virology Reference Centre for Canada (FVRC)

 

Publications

  • Nasheri N, Harlow J, Chen, A, Corneau N, Bidawid S. Survival and Inactivation of Foodborne Viruses in Low Moisture Foods. (in press, Food Microbiology)
  • Nasheri N, Doctor T, Chen A, Harlow J, Gill A. 2020. Evaluation of High-Pressure Processing (HPP) in inactivation of the Hepatitis E Virus. Frontiers in Microbiology. 24;11:461
  • Nasheri N, Harlow J, Chen A, Corneau N, Bidawid S. 2020 Evaluation of Bead-Based Assays in the Isolation of Foodborne Viruses from Low-Moisture Foods. Food Protection 83(3):388
  • Nasheri N, Verster A, Petronella. 2019. Persistence and transmission of pathogenic enteric viruses in frozen produce. Epidemiology & Infection 147, e291,
  • Suresh M, Harlow J, Nasheri N. 2019. Evaluation of porcine gastric mucin assay for detection and quantification of human norovirus in fresh herbs and leafy vegetables. Food Microbiology 84:103254
  • Petronella P, Ronholm J, Suresh M, Harlow J, Myckytczuk O, Corneau N, Bidawid S, Nasheri N. 2018. Genetic characterization of norovirus GII.4 variants circulating in Canada using a metagenomic technique. BMC Infectious Diseases. 18(1):521
  • Mykytczuk O, Harlow J, Bidawid S, Corneau N, Nasheri N. 2017. Prevalence and molecular characterization of the hepatitis E virus in retail pork products marketed in Canada. Food and Environmental Virology. 9(2):208-218
  • Nasheri N, Ronholm J, Petronella N, Bidawid S, Corneau N. 2017. Characterization of the genomic diversity of norovirus in linked patients using a metagenomics deep sequencing approach. Frontiers in Microbiology 8:73
  • Ronholm, J. Nasheri, N. Petronella, N, Pagotto F. 2016. Navigating microbiological food safety in the era of whole genome sequencing. Clinical Microbiology Reviews. 29(4):837-857
  • Nasheri N, Ning Z, Figeys D, Goto N, Pezacki JP. 2015. Activity-based profiling of the proteasome pathway during hepatitis C virus infection. Proteomics. 5(22):3815-3825
  • Desrochers GF, Sherratt AR, Blais DR, Nasheri N, Ning Z, Figeys D, Pezacki JP. 2015. Profiling kinase activity during hepatitis C virus replication using a Wortmannin probe. ACS Infectious Diseases. 1 (9): 443–452
  • Nasheri N, McKay CS, Fulton K, Twine S, Powdrill MH, Pezacki JP. 2014. Hydrophobic triaryl-substituted β-lactams as activity-based probes for profiling eukaryotic enzymes and host–pathogen interactions. ChemBioChem. 15(15): 2195-2200. The article was chosen for the cover.
  • Sherratt AR, Nasheri N, McKay CS, O'Hara S, Hunt A, Ning Z, Figeys D, Pezacki JP. 2014. A new chemical probe for phosphatidylinositol kinase activity. Chembiochem. 15(9):1253-1256
  • Singaravelu R, Chen R, Lyn RK, Jones DM, O'Hara S, Rouleau Y, Cheng J, Srinivasan P, Nasheri N, Russell RS, Tyrrell LD, Pezacki JP. 2013. Hepatitis C virus induced up-regulation of microRNA-27: A novel mechanism for hepatic steatosis. Hepatology, 59(1):98-108. The article was chosen for the cover.
  • Nasheri N, Joyce M, Rouleau Y, Yao S, Tyrrell L, Pezacki JP. 2013. Modulation of fatty acid synthase enzyme activity and expression during hepatitis C virus replication. Chemistry and Biology, 20(4):570-582. The article was chosen for the cover.
  • Singaravelu R, Nasheri N, Sherratt A, Pezacki JP. 2012. Systems biology methods help develop a better understanding of HCV-induced liver injury. Hepatology, 56(1):1-4
  • Blais D, Nasheri N, McKay C, Legault M, Pezacki JP. 2012. Activity-based protein profiling of host-virus interactions. Trends in Biotechnology, 30(2):89-99
  • Cheng J, Danielson D, Nasheri N, Singaravelu R, Pezacki JP. 2011. Enhanced specificity of the viral suppressor of RNA silencing protein P19 towards sequestering of human microRNA-122. Biochemistry, 50(36): 7745-7755
  • Nasheri N, Cheng J, Singaravelu R, Wu P, McDermott M, Pezacki JP. 2011. A novel enzyme-linked assay for miRNAs involving the viral suppressor of RNA silencing p19. Analytical Biochemistry, 412(2):165-172
  • Nasheri N, Singaravelu R, Goodmurphy M, Lyn R, Pezacki JP. 2011. Competing roles of microRNA-122 recognition elements in hepatitis C virus RNA. Virology, 410(2):336-344 
  • Sagan SM, Nasheri N, Luebbert C, Pezacki JP. 2010. The Efficacy of siRNAs against Hepatitis C Virus is strongly influenced by structure and target site accessibility. Chemistry and Biology, 17(5):515-527

 


 

Fields of Interest

  • Virology
  • Food and Environmental Virology
  • Genomics
  • Applied Microbiology
  • Microbiology
Back to top