Candidatures et postes

Informations générales :

Le laboratoire du Dr. Jasmin est un laboratoire au rythme rapide et extrêmement productif, engagé dans l'excellence de la recherche, et nous recherchons actuellement un technicien à temps partiel pour aider à l'un de nos nombreux projets.

En raison des restrictions de covidage (c'est-à-dire le nombre de personnes autorisées à travailler à un moment donné dans le laboratoire), nous ne pouvons offrir qu'un contrat à temps partiel pour le moment.

Le poste est axé sur la biologie moléculaire et le traitement du cancer, plus particulièrement du rhabdomyosarcome.

Les candidats doivent être titulaires d'une maîtrise en biologie cellulaire et moléculaire ou dans un domaine connexe et posséder une expertise en culture de cellules de mammifères, en Western blot et en qPCR, ainsi que d'autres techniques de biologie cellulaire connexes. L'expérience de la microscopie fluorescente et confocale, ainsi que de la manipulation de souris, est un atout, mais n'est pas obligatoire car une formation peut être dispensée.

Si vous êtes intéressé(e) ou connaissez quelqu'un qui l'est, veuillez envoyer votre CV au Dr Shekoufeh Almasi à l'adresse salmasi@uottawa.ca.

Location:

Location: Neural Regeneration Laboratory (NRL) and the India Taylor Lipidomic Research Platform,
Department of Biochemistry, Microbiology, and Immunology at the University of Ottawa (Roger Guindon
Campus, 451 Smyth Road)

Typical tasks and Duties:

• Extracting lipids from patient plasma and cerebrospinal fluid and from mouse biofluids and tissues 
• Preparing solvent systems required for lipidomic mass spectrometry 
• Changing and monitoring N2, CO2, and zero gas dewars and cylinders
• Preparing internal standards for lipidomics 
• Running and analyzing LC-ESI-MS/MS lipidomic experiments 
• Providing technical assistance to students and academic staff 
• Training and oversight of undergraduate and graduate students in lipid extractions 
• Evaluating data and preparing technical reports 
• Selecting and using appropriate procedures, equipment and standards to produce required data and assisting in their
  interpretation 
• Providing technical assistance to students and academic staff 
• Training and oversight of undergraduate and graduate students in necessary cell culture and mouse techniques 
• Ordering and receiving all supplies and track expenditures and obtain quotes for equipment 
• Ensuring all safety procedures are followed and providing orientation of new staff and students

Eligibility: Knowledge, skills, education, and experience:

• M.Sc. degree in a relevant discipline or B.Sc. degree in relevant discipline with minimum 2 years of relevant technical
  and research experience 
• Knowledge and documented experience in lipid biochemistry and/or LC-ESI-MS/MS 
• Knowledge of laboratory maintenance procedures, sterilization techniques, and regulations concerning
  decontamination and disposal of biohazardous material (as applicable) 
• Strong organizational and computer database management skills 
• This position requires detailed record-keeping, time management, and maintenance of detailed written logs  
• Knowledge of and experience in safe laboratory practices 
• Excellent written and verbal communication skills

Equity, Diversity, and Inclusion (EDI) Priority Hiring:

Compensation:

This is a full-time 35 h per week position. You will be offered a 1 yr contract including an initial 3 month
probationary period. Details of our benefit packages for a “medium-term employee” can be found here. Base annual starting
salary will be between $47,150 and $60,597 (35 h work week) depending on experience.

To apply:

Send your CV and contact information of two references to Dr Steffany Bennett at sbennet@uottawa.ca. If you are
a new university graduate without relevant work experience seeking a technical position, please include scanned copies of
your graduate and undergraduate transcripts.

Location:

Location: Neural Regeneration Laboratory (NRL) and the India Taylor Lipidomic Research Platform,
Department of Biochemistry, Microbiology, and Immunology at the University of Ottawa (Roger Guindon
Campus, 451 Smyth Road)

Typical tasks and Duties:

• Maintenance of primary and secondary cell cultures and set up of cell culture experiments as necessary 
• Establishment, propagation, and differentiation of induced pluripotent stem cells into neurons and glia 
• Aiding in colony management of mouse colonies (with ACVS), dissection, genotyping, and behavioural assessment 
• Evaluating data and preparing technical reports 
• Selecting and using appropriate procedures, equipment and standards to produce required data and assisting in their interpretation 
• Providing technical assistance to students and academic staff 
• Training and oversight of undergraduate and graduate students in necessary cell culture and mouse techniques 
• Ordering and receiving all supplies and track expenditures and obtain quotes for equipment 
• Ensuring all safety procedures are followed and providing orientation of new staff and students

Eligibility: Knowledge, skills, education, and experience:

• M.Sc. degree in a relevant discipline or B.Sc. degree in relevant discipline with minimum 2 years of relevant technical and research experience 
• Knowledge and documented experience in cell culture techniques and preferably in induced pluripotent stem cell establishment, propagation, and differentiation is required 
• Experience in handling experimental animals, DNA extraction, PCR analyses is an asset 
• Knowledge of laboratory maintenance procedures, sterilization techniques, and regulations concerning decontamination and disposal of biohazardous material (as applicable) Strong organizational and computer database management skills 
• This position requires detailed record-keeping, time management, and maintenance of detailed written logs 
• Knowledge of and experience in safe laboratory practices 
• Excellent written and verbal communication skills

Equity, Diversity, and Inclusion (EDI) Priority Hiring:

Compensation:

This is a full-time 35 h per week position. You will be offered a 1 yr contract including an initial 3 month
probationary period. Details of our benefit packages for a “medium-term employee” can be found here. Base annual starting
salary will be between $47,150 and $60,597 (35 h work week) depending on experience.

To apply:

Send your CV and contact information of two references to Dr Steffany Bennett at sbennet@uottawa.ca. If your are
a new university graduate without relevant work experience seeking a technical position, please include scanned copies of
your graduate and undergraduate transcripts.

Location:

Location: Neural Regeneration Laboratory (NRL) and the India Taylor Lipidomic Research Platform,
Department of Biochemistry, Microbiology, and Immunology at the University of Ottawa (Roger Guindon
Campus, 451 Smyth Road)

Specific Duties:

Laboratory and Operations Management

• Oversee the planning and scheduling of laboratory activities, including the setting up and running of planned experiments and ensuring that experiments are appropriately supervised and supported. 
• Oversee the operation, maintenance, and management of the laboratory’s research environment.

Financial Operations

• Order all supplies and track expenditures and obtain quotes for equipment. 
• Ensure that all laboratory financial operations comply with university and sponsor requirements. 
• Verify that expenses have been correctly charged, making corrections as necessary. 

Personnel supervision and management 

• Ensure personnel are competent to perform analytical procedures overseeing all operational, technical, safety and regulatory compliance matters within the laboratory. 
• Supervise research activities of staff and students working in the laboratory including orientation of new staff and students. 
• Monitor operations to ensure compliance and ensures that all non-compliant activities are stopped until compliance is assured. 
• Evaluate performance of research staff, assistants, students and volunteers in NRL.

Scientific Operations and Management

• Perform LC-ESI-MS/MS experiments. 
• Use and expand our bioinformatic tools to service our laboratory’s research and our contract fee for service lipidomic analyses. 
• Manage and perform our quality control and quality assurance procedures, including mass spectrometry maintenance and calibration and identify problems as they occur. 
• Identify and troubleshoot research questions or problems which affect the conduct of the project and/or the participation of research subjects, providing leadership in resolving the situation. 
• Prepare key documents including ethics applications, manuscripts for publication, project reports, abstracts, scientific posters and presentations, etc. 
• Liaise with our project partners, network participants, sponsors, government and external agencies etc. on behalf of the laboratory. 
• Assist in the preparation of research publications and presentations.

Regulatory Management

• You will ensure awareness of and adherence to all applicable regulatory requirements by all technical and operational staff, students and authorized equipment users, including regulations applying to human and animal subjects, hazardous materials, radiation, controlled goods, etc.

Knowledge, skills, education and experience:

Knowledge, skills, education and experience:

• You must have a Ph.D. in a relevant discipline (i.e., Biochemistry, Chemistry) or an M.Sc. with three to five years experience in management and supervision of “omics” research.
• You must have knowledge of policies and procedures and regulations regarding laboratory operations
• You must have excellent communication skills. 
• You must have advanced written and verbal skills in English or French. Bilingualism, spoken and written, is preferred.

Core competencies

There are four core competencies for this position:

1. A demonstrated capacity to manage a laboratory (financial, equipment, environment, and staff). 
2. A strong working knowledge of Matlab, Python, and/or R with demonstrated bioinformatic experience. 
3. A strong working knowledge of liquid chromatography and mass spectrometry with demonstrated applied experience. 
4. A strong research background in lipid biochemistry.

We are a collaborative team able to train a highly motivated scientists in each competency. You must have
at least one competency to apply.

Equity, Diversity, and Inclusion (EDI) Priority Hiring:

Compensation:

This is a full-time 35 h per week position. You will be offered a 2 yr contract with benefits
including an initial 6 month probationary period. Details of our benefit packages, can be found here. Base
annual starting salary will range between $79,300 and $88,500 (35 h work week). Starting salary will
depending on your starting core competencies. You will receive yearly performance-based increases and
cost of living increases following performance appraisal.

To apply:

Please indicate the position you are applying for in your cover letter and highlight why you are the
best candidate for the job. We are excited to meet you! Send your CV and contact information of two
references to Dr Steffany Bennett at sbennet@uottawa.ca. We are seeking to recruit for start date of Feb
1 2021. This position will remain open until filled.

The Baetz lab is looking for more members to join our team to work on a variety of projects, including exploiting yeast to understand basic mechanisms of cancer and bio-product development.  Positions available:

Description:

Research Associate or PDF:  We are seeking TWO self-motivated and enthusiastic Research Associate or Postdoctoral fellow to work in the area of stress biology, cellular metabolism and cancer research.  Postdoctoral fellows interested in careers in biotechnology may be interested in leading one of our industrial projects in yeast bioproduct fermentation.  You are a highly innovative scientist with a proven track-record in biochemistry and molecular biology.  Ideally you have a  background in yeast genetics and /or functional genomics or gung-ho to learn. The successful candidate will be required to plan experiments, analyze and interpret data, and effectively communicate results.   The candidate should be able to demonstrate a record of a strong work ethic, successful supervision of trainees, while being in a cooperative and fast-paced work environment.

Basic Requirements:

Education:

PhD in Molecular Biology or Biochemistry (or closely related field). Preference will be given to candidates with experience in Saccharomyces cerevisiae research and/or cell cycle or metabolism research.

Qualifications/Required Skills/Experience:

• Expertise in a variety of basic and specialized laboratory techniques and procedures, including advanced microscopy, qPCR, protein purification, CRISPR and cloning.  Preference will be given to candidates with yeast genetics or functional genomics expertise.
• Experience microbiological techniques
• Skills and/or experience supervising and training students
• Ability to prioritize tasks, meet deadlines and manage multiple projects simultaneously
• Ability to learn and integrate new techniques & methodologies
• Strong analytical, problem solving and critical thinking skills
• Outstanding interpersonal and organizational skills.
• Strong communications skills required, including demonstrated ability to prepare publications independently.

Description:

Technician:  The Baetz lab is looking for a research technician who is eager to join a fast paced team.  Working under the direction of the Principal Investigator and senior research staff, you will be working on a variety of molecular biology and biochemistry tasks to support numerous research projects.  The successful candidate will be required to execute basic biomedical experiments in collaboration with senior researchers and be willing to learn a variety of techniques.  Technician will also be responsible for general laboratory upkeep, including buffer preparation, media making, and ordering and lab maintenance.  This position requires detailed record keeping and time management. 

Education:

BSc or college degree in Biochemistry, Molecular Genetics or closely related field.

Qualifications/Required Skills/Experience:

• Basics in microbiology techniques, including bacteria/fungi culturing.
• Basics in Molecular biology techniques including knowledge of genomic extracts, PCR, cloning and plasmid manipulations
• Basics in protein biochemistry, including wester blotting (SDS-PAGE)
• Demonstrated knowledge of preparing stock buffers and media preparation.
• Ability to learn and integrate new techniques & methodologies
• Detailed oriented and ability to multi-task
• Ability to work within a team.

To apply:

If any of these jobs interest you, please send your Cover Letter, CV and names of three references to kbaetz@uottawa.ca  

The Baetz lab is also continually recruiting new graduate students. 

Description:

The focus of the project is on the large-scale analysis of multi-omics datasets from human gut microbiome in the context of pediatric inflammatory bowel diseases. The goal of the project is to integrate the results of metagenomics, metatranscriptomics and metaproteomics datasets in a machine learning framework to identify predictive signatures of treatment responses in inflammatory bowel disease patients and classify them accordingly.

This research will take place at the Faculty of Medicine of the University of Ottawa. Ottawa is considered to be one of the best livable cities on the globe.

Basic Requirements:

Basic Requirements (Education/Experience):

The ideal candidate should:

• Have a Ph.D. in Bioinformatics, Computational Biology, Machine Learning, Biostatistics, Genomics, or a related field
• Have experience with omics data analysis from next-generation sequencing technologies
• Have knowledge and experience with large-scale biological data analysis
• Have experience in analyzing clinical datasets
• Have experience in the computational analysis of large biological datasets such as ENCODE and TCGA.
• Be experienced with machine learning techniques applied to large biological datasets
• Have proficiency in a programming language such as Java, C, C++, Python, R or Matlab.
• Be comfortable in a Linux environment.
• Be a team player
• Have the ability to work independently
• Have strong written and verbal communication skills and a good ability to communicate with colleagues in biological sciences
• Have a strong publication record.Additional assets considered for this position:
• Have experience in proteomics data analysis
• Have a working knowledge of annotation databases such as Gene Ontology, GeneCards, Ensembl, and Reactome
• Have experience working in a collaborative and multidisciplinary team environment

Start date and Salary:

Start Date: As soon as possible

Salary: $50,000 CAD/year with benefits

To apply:

Please submit a complete CV, a cover letter and the names and contact information of three references to Dr. Mathieu Lavallée-Adam at this address: mathieu.lavallee@uottawa.ca