Career Opportunities

Location:

Location: Neural Regeneration Laboratory (NRL) and the India Taylor Lipidomic Research Platform,
Department of Biochemistry, Microbiology, and Immunology at the University of Ottawa (Roger Guindon
Campus, 451 Smyth Road)

Typical tasks and Duties:

• Extracting lipids from patient plasma and cerebrospinal fluid and from mouse biofluids and tissues
• Preparing solvent systems required for lipidomic mass spectrometry
• Changing and monitoring N2, CO2, and zero gas dewars and cylinders
• Preparing internal standards for lipidomics
• Running and analyzing LC-ESI-MS/MS lipidomic experiments
• Providing technical assistance to students and academic staff
• Training and oversight of undergraduate and graduate students in lipid extractions
• Evaluating data and preparing technical reports
• Selecting and using appropriate procedures, equipment and standards to produce required data and assisting in their
  interpretation
• Providing technical assistance to students and academic staff
• Training and oversight of undergraduate and graduate students in necessary cell culture and mouse techniques
• Ordering and receiving all supplies and track expenditures and obtain quotes for equipment
• Ensuring all safety procedures are followed and providing orientation of new staff and students

Eligibility: Knowledge, skills, education, and experience:

• M.Sc. degree in a relevant discipline or B.Sc. degree in relevant discipline with minimum 2 years of relevant technical
  and research experience
• Knowledge and documented experience in lipid biochemistry and/or LC-ESI-MS/MS
• Knowledge of laboratory maintenance procedures, sterilization techniques, and regulations concerning
  decontamination and disposal of biohazardous material (as applicable)
• Strong organizational and computer database management skills
• This position requires detailed record-keeping, time management, and maintenance of detailed written logs
• Knowledge of and experience in safe laboratory practices
• Excellent written and verbal communication skills

Equity, Diversity, and Inclusion (EDI) Priority Hiring:

Compensation:

This is a full-time 35 h per week position. You will be offered a 1 yr contract including an initial 3 month
probationary period. Details of our benefit packages for a “medium-term employee” can be found here. Base annual starting
salary will be between $47,150 and $60,597 (35 h work week) depending on experience.

To apply:

Send your CV and contact information of two references to Dr Steffany Bennett at sbennet@uottawa.ca. If you are
a new university graduate without relevant work experience seeking a technical position, please include scanned copies of
your graduate and undergraduate transcripts.

Location:

Location: Neural Regeneration Laboratory (NRL) and the India Taylor Lipidomic Research Platform,
Department of Biochemistry, Microbiology, and Immunology at the University of Ottawa (Roger Guindon
Campus, 451 Smyth Road)

Typical tasks and Duties:

• Maintenance of primary and secondary cell cultures and set up of cell culture experiments as necessary
• Establishment, propagation, and differentiation of induced pluripotent stem cells into neurons and glia
• Aiding in colony management of mouse colonies (with ACVS), dissection, genotyping, and behavioural assessment
• Evaluating data and preparing technical reports
• Selecting and using appropriate procedures, equipment and standards to produce required data and assisting in their interpretation
• Providing technical assistance to students and academic staff
• Training and oversight of undergraduate and graduate students in necessary cell culture and mouse techniques
• Ordering and receiving all supplies and track expenditures and obtain quotes for equipment
• Ensuring all safety procedures are followed and providing orientation of new staff and students

Eligibility: Knowledge, skills, education, and experience:

• M.Sc. degree in a relevant discipline or B.Sc. degree in relevant discipline with minimum 2 years of relevant technical and research experience
• Knowledge and documented experience in cell culture techniques and preferably in induced pluripotent stem cell establishment, propagation, and differentiation is required
• Experience in handling experimental animals, DNA extraction, PCR analyses is an asset
• Knowledge of laboratory maintenance procedures, sterilization techniques, and regulations concerning decontamination and disposal of biohazardous material (as applicable)Strong organizational and computer database management skills
• This position requires detailed record-keeping, time management, and maintenance of detailed written logs
• Knowledge of and experience in safe laboratory practices
• Excellent written and verbal communication skills

Equity, Diversity, and Inclusion (EDI) Priority Hiring:

Compensation:

This is a full-time 35 h per week position. You will be offered a 1 yr contract including an initial 3 month
probationary period. Details of our benefit packages for a “medium-term employee” can be found here. Base annual starting
salary will be between $47,150 and $60,597 (35 h work week) depending on experience.

To apply:

Send your CV and contact information of two references to Dr Steffany Bennett at sbennet@uottawa.ca. If your are
a new university graduate without relevant work experience seeking a technical position, please include scanned copies of
your graduate and undergraduate transcripts.

Location:

Location: Neural Regeneration Laboratory (NRL) and the India Taylor Lipidomic Research Platform,
Department of Biochemistry, Microbiology, and Immunology at the University of Ottawa (Roger Guindon
Campus, 451 Smyth Road)

Specific Duties:

Laboratory and Operations Management

• Oversee the planning and scheduling of laboratory activities, including the setting up and running of planned experiments and ensuring that experiments are appropriately supervised and supported. 
• Oversee the operation, maintenance, and management of the laboratory’s research environment.

Financial Operations

• Order all supplies and track expenditures and obtain quotes for equipment. 
• Ensure that all laboratory financial operations comply with university and sponsor requirements. 
• Verify that expenses have been correctly charged, making corrections as necessary. 

Personnel supervision and management 

• Ensure personnel are competent to perform analytical procedures overseeing all operational, technical, safety and regulatory compliance matters within the laboratory. 
• Supervise research activities of staff and students working in the laboratory including orientation of new staff and students.
• Monitor operations to ensure compliance and ensures that all non-compliant activities are stopped until compliance is assured. 
• Evaluate performance of research staff, assistants, students and volunteers in NRL.

Scientific Operations and Management

• Perform LC-ESI-MS/MS experiments. 
• Use and expand our bioinformatic tools to service our laboratory’s research and our contract fee for service lipidomic analyses. 
• Manage and perform our quality control and quality assurance procedures, including mass spectrometry maintenance and calibration and identify problems as they occur. 
• Identify and troubleshoot research questions or problems which affect the conduct of the project and/or the participation of research subjects, providing leadership in resolving the situation. 
• Prepare key documents including ethics applications, manuscripts for publication, project reports, abstracts, scientific posters and presentations, etc. 
• Liaise with our project partners, network participants, sponsors, government and external agencies etc. on behalf of the laboratory. 
• Assist in the preparation of research publications and presentations.

Regulatory Management

• You will ensure awareness of and adherence to all applicable regulatory requirements by all technical and operational staff, students and authorized equipment users, including regulations applying to human and animal subjects, hazardous materials, radiation, controlled goods, etc.

Knowledge, skills, education and experience:

Knowledge, skills, education and experience:

• You must have a Ph.D. in a relevant discipline (i.e., Biochemistry, Chemistry) or an M.Sc. with three to five years experience in management and supervision of “omics” research.
• You must have knowledge of policies and procedures and regulations regarding laboratory operations
• You must have excellent communication skills. 
• You must have advanced written and verbal skills in English or French. Bilingualism, spoken and written, is preferred.

Core competencies

There are four core competencies for this position:

1. A demonstrated capacity to manage a laboratory (financial, equipment, environment, and staff). 
2. A strong working knowledge of Matlab, Python, and/or R with demonstrated bioinformatic experience. 
3. A strong working knowledge of liquid chromatography and mass spectrometry with demonstrated applied experience. 
4. A strong research background in lipid biochemistry.

We are a collaborative team able to train a highly motivated scientists in each competency. You must have
at least one competency to apply.

Equity, Diversity, and Inclusion (EDI) Priority Hiring:

Compensation:

This is a full-time 35 h per week position. You will be offered a 2 yr contract with benefits
including an initial 6 month probationary period. Details of our benefit packages, can be found here. Base
annual starting salary will range between $79,300 and $88,500 (35 h work week). Starting salary will
depending on your starting core competencies. You will receive yearly performance-based increases and
cost of living increases following performance appraisal.

To apply:

Please indicate the position you are applying for in your cover letter and highlight why you are the
best candidate for the job. We are excited to meet you! Send your CV and contact information of two
references to Dr Steffany Bennett at sbennet@uottawa.ca. We are seeking to recruit for start date of Feb
1 2021. This position will remain open until filled.

The Baetz lab is looking for more members to join our team to work on a variety of projects, including exploiting yeast to understand basic mechanisms of cancer and bio-product development.Positions available:

Description:

Research Associate or PDF:

We are seeking TWO self-motivated and enthusiastic Research Associate or Postdoctoral fellow to work in the area of stress biology, cellular metabolism and cancer research.

Postdoctoral fellows interested in careers in biotechnology may be interested in leading one of our industrial projects in yeast bioproduct fermentation.

You are a highly innovative scientist with a proven track-record in biochemistry and molecular biology. Ideally you have a background in yeast genetics and /or functional genomics or gung-ho to learn. The successful candidate will be required to plan experiments, analyze and interpret data, and effectively communicate results. The candidate should be able to demonstrate a record of a strong work ethic, successful supervision of trainees, while being in a cooperative and fast-paced work environment.

Basic Requirements:

Education:

PhD in Molecular Biology or Biochemistry (or closely related field). Preference will be given to candidates with experience in Saccharomyces cerevisiaeresearch and/or cell cycle or metabolism research.

Qualifications/Required Skills/Experience:

• Expertise in a variety of basic and specialized laboratory techniques and procedures, including advanced microscopy, qPCR, protein purification, CRISPR and cloning.
• Preference will be given to candidates with yeast genetics or functional genomics expertise.
• Experience microbiological techniques
• Skills and/or experience supervising and training students
• Ability to prioritize tasks, meet deadlines and manage multiple projects simultaneously
• Ability to learn and integrate new techniques & methodologies
• Strong analytical, problem solving and critical thinking skills
• Outstanding interpersonal and organizational skills.
• Strong communications skills required, including demonstrated ability to prepare publications independently.

Description:

Technician: The Baetz lab is looking for a research technician who is eager to join a fast paced team. Working under the direction of the Principal Investigator and senior research staff, you will be working on a variety of molecular biology and biochemistry tasks to support numerous research projects. The successful candidate will be required to execute basic biomedical experiments in collaboration with senior researchers and be willing to learn a variety of techniques. Technician will also be responsible for general laboratory upkeep, including buffer preparation, media making, and ordering and lab maintenance. This position requires detailed record keeping and time management.

Education:

BSc or college degree in Biochemistry, Molecular Genetics or closely related field.

Qualifications/Required Skills/Experience:

• Basics in microbiology techniques, including bacteria/fungi culturing.
• Basics in Molecular biology techniques including knowledge of genomic extracts, PCR, cloning and plasmid manipulations
• Basics in protein biochemistry, including wester blotting (SDS-PAGE)
• Demonstrated knowledge of preparing stock buffers and media preparation.
• Ability to learn and integrate new techniques & methodologies
• Detailed oriented and ability to multi-task
• Ability to work within a team.

To apply:

If any of these jobs interest you, please send your Cover Letter, CV and names of three references to kbaetz@uottawa.ca

The Baetz lab is also continually recruiting new graduate students.

General Information:

Applications are invited for a postdoctoral fellowship starting immediately at the University of Ottawa to investigate features of synaptic signal integration and microcircuit function using experimental and computational approaches. The researcher will join a collaborative group with expertise in cellular electrophysiology, two-photon imaging, and advanced computational modelling and statistical processing (Drs Katalin Toth and Richard Naud). Expertise in cellular electrophysiology and/or in two-photon cellular imaging is required. This fully funded position with attractive conditions is available immediately. The candidate is expected to be competitive for external fellowships.

The researcher will join uOttawa’s Brain and Mind Research Institute’s Center for Neural Dynamics (Department of Cellular and Molecular Medicine; Faculty of Medicine). uOttawa’s Neuroscience community is fast expanding, highly dynamic and offers a rich array of collaborative opportunities. Ottawa, the capital of Canada, is a green, multi-cultural city that offers the highest standard of living in the country and is second worldwide for quality of life (Numbeo index, 2015). The city has many parks including the Unesco World Heritage Rideau Canal and is surrounded by an extensive greenbelt. This bilingual, culturally-rich city lies along the border between the province of Quebec and Ontario and is within driving distance to Montréal and Toronto.

Employer Profile:

The University of Ottawa is a bilingual research university in Ottawa, Ontario, Canada. The university offers a wide variety of academic programs, administered by ten faculties. It is a member of the U15, a group of research-intensive universities in Canada. In the Maclean’s 2015 Canadian University rankings, the University of Ottawa ranked 2nd for Medical/Science Grants, 2nd for Scholarships & Bursaries and 1st for Student Services in the Medical/Doctoral University category.

Please send CV, statement of research interest and names of three references to: Katalin Toth (ktoth@uottawa.ca).

General Information:

The laboratory of Dr. Jasmin is a fast paced and extremely productive lab committed to excellence in research, and we are currently looking for a part-time technician to help with one of our many projects. 

Due to covid restrictions (i.e. the number of people allowed to work at any one point within the laboratory), we can only offer a part-time contract at this time. 

This position will involve a cancer related project, so experience in this field would be an asset but not required. 

The successful candidate however, should have experience with Mammalian Cell Culture, Protein extraction and quantification, Western blot, RNA extraction and quantification, PCR, and qPCR as well as other cell biology techniques. 

Working with and handling mice will also be required, so previous experience would be an asset but not required as training can be provided. 

If you are interested or know of someone who is, please send your CV to Dr. Shekoufeh Almasi at salmasi@uottawa.ca 

General Information:

Posting No.: RPF1931

Start date: June 2020

Employment Status: Temporary full-time (8 hours/day), 12 months

Unit/Department: Research

Program: Cardiac Translational Research Lab

Number of Vacancies: 1

Wage: $43,000/year

Function: Full-time laboratory post-doctoral fellowship position available from June 1, 2020. The lab focuses on stem cells, exosomes, regeneration and cardiac electrophysiology.

Responsibilities:

• Perform sterile tissue culture techniques to grow and maintain cells,
• Perform flow cytometry, FISH and PCR analysis and in vivo experiments,
• Perform immunostaining/immunohistochemistry and help optimize techniques.
• Analyze data and maintain clear and accurate data records.
• Use sterile techniques to avoid contaminating lab experiments.
• Independently identifying additional tasks (other than those assigned) which need to be performed.
• Use appropriate safety procedures for handling, storage, and disposal of biohazards,
• Assist in the training of new lab personnel. 
• Edit scientific papers.
• Pre-surgical preparation (including pre-anesthetic induction, intubation, sterile preparation of animal and instruments),
• Surgical assistance (anesthesia, circulation and scrub nursing),
• Post-operative recovery of animals, daily drug administration

Basic Requirements:

• The candidate should have strong knowledge of and experience with cell culture
• Experience with vector/cloning, viral vector preparation, gene cloning, site directed mutagenesis, PCR and protein biochemistry is preferred.
• Research lab experience
• PhD or MD degree

Suitability and Preferred Qualifications:

Suitability:

• Excellent interpersonal relations and communications skills, sound judgment and ability to foster a cooperative work environment
• Strong ability to multitask
• High level of adaptability 
• Attention to detail
• Ability to learn and integrate new techniques & methodologies 

Preferred Qualifications:

The candidate should be able to demonstrate a record of a strong work ethic and enthusiasm to work independently while being part of a research team.

Accommodations will be provided in all parts of the hiring process relating to any specialty requirements. Applicants should make their needs known in advance.

The successful candidate will be required, prior to the start of employment, to complete mandatory organizational training available online, provide a satisfactory Criminal Record Check and provide an official piece of photo identification.

Qualified candidates should send a short letter of introduction describing their career path and previous expertise, CV, and the names of three references to jobpostings@ottawaheart.ca.

Description:

The Baetz lab is looking for a scientifically strong, self-motivated and enthusiastic Research Associate to work in the area of stress biology, cellular metabolism and cancer research.  You are a highly innovative scientist with a proven track-record in biochemistry and molecular biology, ideally with a background in yeast genetics and /or functional genomics. The successful candidate will be required to plan experiments, analyze and interpret data, and effectively communicate results.   The candidate should be able to demonstrate a record of a strong work ethic, successful supervision of trainees, while being in a cooperative and fast-paced work environment.

Basic Requirements:

Basic Requirements (Education/Experience:

• PhD in Molecular Biology or Biochemistry (or closely related field) and Postdoctoral or work experience in an intensive research environment. Preference will be given to candidates with experience in Saccharomyces cerevisiae research and/or cell cycle or metabolism research.
• Expertise in a variety of basic and specialized laboratory techniques and procedures, including advanced microscopy, qPCR, protein purification, CRISPR and cloning.  Preference will be given to candidates with yeast genetics or functional genomics expertise.
• Experience microbiological techniques
• Skills and/or experience supervising and training students
• Ability to prioritize tasks, meet deadlines and manage multiple projects simultaneously
• Ability to learn and integrate new techniques & methodologies
• Strong analytical, problem solving and critical thinking skills
• Outstanding interpersonal and organizational skills.
• Strong communications skills required, including demonstrated ability to prepare publications independently.
• Statistical experience is an asset, but not essential

Functions:

• In collaboration with Dr Baetz, you will design, develop, and execute laboratory experiments leading your own research project (50%)
• Supervise and train new graduate and undergraduate students (20%)
• General Laboratory management: ordering, maintaining financial records, supervises all aspects of the laboratory including implementation and adherence to all applicable safety regulations and maintaining laboratory equipment (20%)
• Preparation of figures using computer software and writing/editing documents (10%)

To apply:

If this job is right for you and you are ready for the next stage in your career -please send your cover letter, CV and names of three references to kbaetz@uottawa.ca 

General Information:

Postdoctoral positions are available in the laboratory of Dr. Xiaohui Zha at Ottawa Hospital Research Institute/University of Ottawa*, Canada (http://www.ohri.ca/profile/Zha).

Project Description:

The project is to study the mechanisms by which cholesterol regulates macrophage inflammation, a key event in atherosclerosis. Cholesterol, a major component of the plasma membrane in mammalian cells, predominantly regulates membrane physical properties. Most likely through its modulation of cellular membranes, cholesterol impacts numerous signal transduction pathways and cellular processes.  Particularly, cholesterol levels in macrophages determine the nature of the inflammation response, for example, pro-inflammatory response (M1), anti-inflammatory (M2) or anything in between. The mechanism is largely unknown.  In recent years, it is increasingly apparent that macrophages can respond to environmental cues to establish an epigenetically “poised” state.  This allows macrophages to rapidly launch a large-scale gene expression program upon stimulation (i.e. LPS). The project will use biochemistry and genomic techniques, such as RNA-seq and ChIP-seq, to understand how cholesterol establishes epigenetically “poised” states in the genome of the macrophages to regulate gene expression for inflammatory responses.

Basic Requirements:

Candidates should be a fresh PhD (less than two years since graduation) in physical science or biological science with good publication record.  Knowledge/experience in genomic system biology is a plus, but not necessary.  If interested, please send curriculum vitae and brief statement of research interest to xzha@ohri.ca .

Contact info:

Xiaohui Zha, Senior Scientist
Chronic Disease Program
Ottawa Hospital Research Institute
501 Smyth Road, Ottawa, ON K1H 8L6
 

*The Ottawa Hospital Research Institute is the research arm of The Ottawa Hospital and an affiliated institute of the University of Ottawa. With more than 1,700 scientists, clinician investigators, trainees and staff, and total revenues of more than $100 million, it is one of the foremost Canadian hospital-based research institutes. Researcher are investigating virtually every major disease and condition, with a focus on answering important health questions and translating our findings into benefits for patients and society.