Woo Jae Kim
Woo Jae Kim
Office: 613-562-5800 ext. 8385
Work E-mail: firstname.lastname@example.org
Overview of Research Interests
In short, the Kim lab is seeking for the fundamental mechanisms how specific neural circuits lead to certain behaviors. We use tiny insect Drosophila melanogaster to answer this question. Dr. Kim has established two behavioral paradigm called ‘Longer-Mating-Duration’ and ‘Shorter-Mating-Duration’. In short term, the Kim lab will focus on identifying functional neural circuits, genetic components, and sensory modality for these behaviors. In mid term, the Kim lab would expand the behavioral repertoires by establishment of automated quantification system of behavior. Beyond this, the Kim lab will establish automated optogenetic & thermogenetic behavioral manipulation system. With the advantage of strong genetic tools available in fruit fly and establishing behavioral quantification and manipulation systems, the Kim lab in the long term will seek for how neural circuits for complex social behavior function in vivo. Reverse engineering to build up eusociality in fruit fly and genomic editing of eusocial insect such as honey bees/ants using CRISPR/Cas9 is also one of the plans to understand social behavior.
Dr. Kim established two behavioral paradigms.
- LMD (Longer-Mating-Duration): males previously exposed to rivals extend their mating duration.
- SMD (Shorter-Mating-Duration): sexually satiated males invest less on mating duration.
Dr. Kim finely mapped the functional neural circuits and genetic components for LMD. The Kim lab will try to linearize the whole functional circuits for this unique behavior. There are no labs working with this behavioral paradigm. Identifying whole circuitry for certain behavior and reconstructing that with reverse genetics will be breakthrough in neuroscience filed and to understand our Brain&Mind.
The lab applied grants from the Canadian Foundation for Innovation (CFI) and will apply Natural Sciences and Engineering Research Council of Canada (NSERC) soon. Kim lab just started July 1st, 2015. We will apply to get funded from various grant sources.