The Core facility offers decalcification, tissue processing, paraffin embedding (agar pre-embedding) and various types of sectioning (routine, serial, levels, and RNAse-free).
After processing, samples are placed in a specific orientation in a mold containing melted paraffin, which hardens and forms a block upon cooling. The block provides support to the tissue when they are cut.
Paraffin sectioning is the technique of cutting thin slices of tissue that has been fixed and embedded in wax using specialized equipment called a microtome. Sections are then flattened in a heated water bath, floated onto slides and dried.