UNIVERSITY OF OTTAWA
L’institut de la Biologie des Systèmes d’Ottawa Ottawa Institute of Systems Biology
2019 Ottawa Institute for Systems Biology Symposium
Nav Centre
May 6 – 7, 2019
Directions: https://goo.gl/maps/yoLVMwVR4692
Address: 1950 Montreal Rd,
Cornwall, ON
K6H 6L2
Need a ride? Have space in your vehicle? Register at:
http://www.groupcarpool.com/t/buzrxc
Talks begin at 10:00am on May 6.
Accommodations Check-in: 2:00pm
Accommodations Checkout: 12:00pm
There is luggage storage in the lobby area.
- All talks will take place in the Plenary D214.
- Poster session will take place in the De Havilland Room
Posters should be 36” x 48”
- All meals will take place in the Propeller Restaurant
Schedule for May 6, 2019
|
9:00-10:00 |
Registration |
|
10:00-10:10 |
Opening Address by Kristin Baetz |
Metabolism: Getting going and keepin’ it running Chair: Mireille Khacho
|
10:10-10:25 |
Elizabeth Walden |
Baetz Lab |
What is the skinny on the fat KAT? - Defining the role of the yeast lysine acetyltransferase NuA4, and its human homolog Tip60, in metabolism |
|
10:30- 10:45 |
Jens Halling |
Visiting scientist |
Colchicine treatment impairs skeletal muscle mitochondrial function and insulin sensitivity in aged mice |
|
10:50 - 11:05 |
Rajaa Sebaa |
Harper Lab |
SIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1 |
|
11:10 - 11:25 |
Nicole Baker |
Khacho Lab |
The role of mitochondrial Opa1 in satellite stem cell function and skeletal muscle regeneration |
|
11:30-12:30 |
Keynote Lecture: Dr. Oliver Fiehn UC Davis |
|
12:30 – 13:30 |
Lunch – Roundtable discussion |
Proteins and PTMs – Charged up and out of site! Chair: Mike Downey
|
13:35 – 13:50 |
Paula Adler |
Figeys Lab |
Therapeutic targeting of casein kinase 1δ/ε in an Alzheimer's disease mouse model |
|
13:55 – 14:10 |
Amanda Bentley-DeSousa |
Downey Lab |
Investigating the regulation of polyphosphate metabolism by the conserved AP3 complex |
|
14:15 – 14:30 |
Natasha Trzaskalski |
Mulvihill Lab |
Identification of Cardioactive Dipeptidyl Peptidase 4 Substrates |
|
14:35 – 14:50 |
Laurence Langlois-LeMay |
D’Amours Lab |
Investigating the role of the polo-like kinase Cdc5 in the adaptation response to DNA damage |
|
14:50-15:10 |
Coffee |
Imaging metabolic pathways Chair: Laura Trinkle-Mulcahy
|
15:10 – 15:25 |
Terry Suk |
Rousseaux Lab |
Systems based approach to uncover regulatory mechanisms of TDP-43 mislocalization in ALS |
|
15:30 – 15:45 |
Danny Salem |
Kaern Lab |
Using the Tandem Fluorescent Timer as a Reporter of Dynamic Gene Regulation
|
|
15:50– 16:05 |
Alexia Kirby |
Shuhendler Lab |
Molecular imaging of aldehydes as bio-markers of injury and disease |
|
16:10 –16:25 |
Adam Pietrobon |
Stanford Lab |
High throughput small molecule screening with 3D lung-mimetic hydrogels in a rare lung disease Lymphangioleiomyomatosis |
|
16:30-18:30 |
Posters + Cocktail Reception |
|
18:30:-20:00 |
Dinner |
|
21:00- |
SOCIAL - Jet Set Pub |
Schedule for May 7, 2019
|
7:00 – 9:00 |
Breakfast |
Bioinformatics - Making sense of “META” Data Chair: Steffany Bennett
|
9:00 – 9:15 |
Reyhaneh Hosseini |
Bickel Lab |
Comparing the methods of combination for the local false discovery rate estimates of gene expression data |
|
9:20 – 9:35 |
Justin Chitpin |
Bennett/Perkins Labs |
Bioinformatics for quantitative lipidomics discovery: Identifying lipids from precursor ion scan and multiple reaction monitoring mass spectrometry using structure-retention time relationships |
|
9:40 – 9:55 |
Janice Ou |
Jeff Xia Lab (McGill) |
mGWAS-Explorer: a comprehensive knowledgebase and analytical platform to study genetically influenced metabotypes |
|
10:00 – 10:15 |
Xuhua Xia |
Xuhua Xia Lab |
RNA-Seq approach for accurate characterization of splicing efficiency of yeast introns |
|
10:20 – 10:40 |
Coffee break |
The Future Is Here! New technologies for understanding metabolism Chair: Mary-Ellen Harper
|
10:45 – 11:00 |
Mary-Ellen Harper |
Harper Lab |
Racehorse vs Workhorse, and other considerations in cellular and mitochondrial respirometry |
|
11:05 – 11:20 |
Meir Menzies |
Menzies Lab |
The better mouse model: using genetic diversity to investigate complex diseases
|
|
11:25 – 11:40 |
David Patten |
Metabolomics Core - St Pierre/Bennett |
The New uOttawa Metabolomics Core Facility: Integrating Targeted, Untargeted and Stable Isotope Tracing Analyses to Your Projects |
|
11:45 – 12:00 |
Hongbin Xu |
Metabolomics Core - St Pierre/Bennett |
Mass spectrometry-based lipidomics for interrogating metabolism |
|
12:30 – 13:30 |
Lunch |
Genome biology: Transcription and repair Chair: Damien D’Amours
|
13:30 – 13:45 |
Yidai Yang |
Couture Lab |
A monovalent zinc binding site stabilizes the integration of Cfp1 into SET1 complexes |
|
13:50 – 14:05 |
Carmen Palii |
Brand Lab |
TAL1 subverts the function of the T-cell regulator BCL11B to induce and maintain T-ALL |
|
14:10 – 14:25 |
Jamie Whitcomb |
Nemer Lab |
Identification of GATA4 Pathways for Transcriptional Regulation of Angiogenesis |
|
14:30-14:45 |
Daniel Robinson |
Dilworth Lab |
Promoter-proximal stalling of RNA-Polymerase II is required for repopulation of the satellite cell niche after muscle injury |
|
14:50 – 15:00 |
Closing remarks and poster awards |
|
15:00 – 15:40 |
PI meeting |