Selected Publications

Alexandre Blais

Nandi S, Blais A, Ioshikhes I. Identification of cis-regulatory modules in promoters of human genes exploiting mutual positioning of transcription factors. Nucleic Acids Res. 2013 Oct;41(19):8822-41. doi: 10.1093/nar/gkt578. Epub 2013 Aug 2.

Liu Y, Chakroun I, Yang D, Horner E, Liang J, Aziz A, Chu A, De Repentigny Y, Dilworth FJ, Kothary R, Blais A. Six1 regulates MyoD expression in adult muscle progenitor cells. PLoS One. 2013 Jun 28;8(6):e67762. doi:10.1371/journal.pone.0067762. Print 2013.

Julian LM, Vandenbosch R, Pakenham CA, Andrusiak MG, Nguyen AP, McClellan KA, Svoboda DS, Lagace DC, Park DS, Leone G, Blais A, Slack RS. Opposing regulation of Sox2 by cell-cycle effectors E2f3a and E2f3b in neural stem cells. Cell Stem Cell. 2013 Apr 4;12(4):440-52. doi: 10.1016/j.stem.2013.02.001. Epub 2013 Mar 14.

Liu Y, Nandi S, Martel A, Antoun A, Ioshikhes I, Blais A. Discovery, optimization and validation of an optimal DNA-binding sequence for the Six1 homeodomain transcription factor. Nucleic Acids Res. 2012 Sep 1;40(17):8227-39. Epub 2012 Jun 22.

Ghanem N, Andrusiak MG, Svoboda D, Al Lafi SM, Julian LM, McClellan KA, De Repentigny Y, Kothary R, Ekker M, Blais A, Park DS, Slack RS. The Rb/E2F pathway modulates neurogenesis through direct regulation of the Dlx1/Dlx2 bigene cluster. J Neurosci. 2012 Jun 13;32(24):8219-30. doi: 10.1523/JNEUROSCI.1344-12.2012.

Ryan T, Liu J, Chu A, Wang L, Blais A, Skerjanc IS. Retinoic acid enhances skeletal myogenesis in human embryonic stem cells by expanding the premyogenic progenitor population. Stem Cell Rev. 2012 Jun;8(2):482-93. doi:10.1007/s12015-011-9284-0.

Liu Y, Chu A, Chakroun I, Islam U, Blais A. Cooperation between myogenic regulatory factors and SIX family transcription factors is important for myoblast differentiation. Nucleic Acids Res. 2010 Nov;38(20):6857-71. doi:10.1093/nar/gkq585. Epub 2010 Jul 2.

Seenundun S, Rampalli S, Liu QC, Aziz A, Palii C, Hong S, Blais A, Brand M, Ge K, Dilworth FJ. UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis. EMBO J. 2010 Apr 21;29(8):1401-11. doi: 10.1038/emboj.2010.37. Epub 2010 Mar 18.

Niro C, Demignon J, Vincent S, Liu Y, Giordani J, Sgarioto N, Favier M, Guillet-Deniau I, Blais A, Maire P. Six1 and Six4 gene expression is necessary to activate the fast-type muscle gene program in the mouse primary myotome. Dev Biol. 2010 Feb 15;338(2):168-82. doi: 10.1016/j.ydbio.2009.11.031. Epub 2009 Dec 4.

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