Collaborative Graduate Program
Pathology and Experimental Medicine (MNP)
This is a collaborative program in Pathology and Experimental Medicine leading to an MSc or PhD degree in one of the primary programs:
The emphasis of this collaborative program is on the training of graduate students in the field of pathology and experimental medicine with the aim of providing them with the knowledge and skills to examine the basic mechanisms of disease pathology, and to develop new strategies for prevention and treatment.
Faculty members include basic and clinical scientists with interests in cancer, emerging pathogens, cardiovascular and neurodegenerative diseases.
Pathology and Experimental Medicine (Collaborative) on the Office of the Vice-Provost, Graduate and Postdoctoral Studies website.
Members of the Collaborative Program
- Christina Addison
- John Bell
- Hsiao-Huei Chen
- Manijeh Daneshmand
- Adolfo deBold
- Mercedes deBold
- Joseph deNanassy
- Jean-Simon Diallo
- Jim Dimitroulakos
- Doug Gray
- Gerard Jansen
- Robert Korneluk
- Ashok Kumar
- Thomas Lagacé
- Qiao Li
- Ian Lorimer
- Celia Marginean
- Michael McBurney
- Bruce McKay
- Jean Michaud
- Ross Milne
- Rudolf Mueller
- Ruth Padmore
- Christine Pratt
- Olga Pulido
- Jean-Marc Renaud
- Luc Sabourin
- Subash Sad
- Michael Schlossmacher
- Erik Suuronen
- Baltwant Tuana
- Barbara Vanderhyden
- John Veinot
- Zemin Yao
- John Woulfe
- Wandong Zhang
Admission
Candidates should indicate in their application form that they wish to be accepted into the collaborative program.
To be admitted students must:
- Be admitted to one of the primary programs participating in the collaborative program.
- The thesis supervisor must be a member of the Pathology and Experimental Medicine program.
For admission questions please contact: grad.med@uottawa.ca
This program is currently under revision. At this time, we are not accepting applications.
Financial Support
All students accepted into the collaborative program will be provided with financial support as per the regulations of the respective primary programs.
Requirements of the Collaborative Program
The curriculum requirements of the primary programs include two courses, a seminar course, and a thesis. Students in the collaborative program must meet the requirements of their primary program by completing one Pathology and Experimental Medicine specialization course as one of the two required courses, the Pathology and Experimental Medicine seminar course in lieu of the primary program seminar course, and a thesis on a research project in the area of Pathology and Experimental Medicine.
Master’s Degree Requirements
The requirements and regulations of both the primary program and of the collaborative program must be met.
The requirements specific to the collaborative program are as follows:
- One course (3 credits) in the primary program.
- One Pathology and Experimental Medicine specialization course (3 credits).
- Successful completion of the Pathology and Experimental Medicine seminar course.
- Presentation and defence of a thesis on a topic in pathology and experimental medicine based on original research carried out under the supervision of a professor who is a member of the Pathology and Experimental Medicine collaborative program. At least one of the thesis examiners must be a member of the Pathology and Experimental Medicine collaborative program.
Transfer from MSc to PhD
The regulations for transfer from MSc to PhD without being required to write a master’s thesis are those in effect in the student’s primary program.
Minimum Standards
The passing grade in all courses is C+. Students who fail two courses (equivalent to 6 credits) must withdraw from the program.
Thesis Advisory Committee (TAC)
The composition of the Thesis Advisory Committee (TAC) and the frequency of committee meetings follow the regulations of the respective primary program. At least one member of the TAC, in addition to the thesis supervisor, must be part of the Pathology and Experimental Medicine collaborative program.
PhD Requirements
The requirements of both the primary program and those of the collaborative program must be met.
The requirements specific to the collaborative program are as follows:
- One course (3 credits) in the primary program.
- One Pathology and Experimental Medicine specialization course (3 credits).
- Successful completion of the Pathology and Experimental Medicine seminar course.
- Successful completion of the Comprehensive Examination as required by the respective primary program.
- Preparation and defense of a thesis under the supervision of a professor who is a member of the Pathology and Experimental Medicine program. The thesis must be relevant to the focus of the Pathology and Experimental Medicine program. At least one of the examiners must be a member of the Pathology and Experimental Medicine collaborative program.
Residence
As per FGPS regulations, all students must complete a minimum of six sessions of full-time registration at the beginning of the program. All requests for non-consecutive full-time study sessions will need to be approved by the FGPS. The program is intended for full-time students.
Minimum Standards
The passing grade in all courses is C+. Students who fail two courses (equivalent to 6 credits), the thesis proposal, or the comprehensive exam or whose research progress is deemed unsatisfactory are required to withdraw.
Thesis Advisory Committee (TAC)
The composition of the Thesis Advisory Committee (TAC) and the frequency of committee meetings follow the regulations of the respective primary program. At least one member of the TAC, in addition to the thesis supervisor, must be part of the Pathology and Experimental Medicine collaborative program.
Specialization Courses
CMM5001
The Pathological Basis of Disease (3 cr.)
An introductory course to general pathology for graduate students in the life sciences. This course teaches fundamental concepts of the basis of disease as viewed from a general pathology perspective. It provides 3-hour weekly lectures during the winter term dealing with manifestation of disease at the macroscopic and microscopic levels. Background lectures are given on the morphology of normal tissues and organs and in investigative approaches used. General Pathology of the following topics is discussed in the different lectures: 1. Hypertrophy, atrophy, hyperplasia, aplasia, metaplasia, dysplasia, neoplasia. 2. Storage diseases. 3. Extracellular space pathologies. 4. Cell injury, necrosis and apoptosis. 5. Inflammation and edema. 6. Repair. 7. Immunopathology. 8. Neoplasia. Benign, malignant. 9. Blood vessels. Hemostasis, thrombosis and embolism. Atherosclerosis and arteriosclerosis. Heart disease. Heart failure, pathological hypertrophy, ischemic heart disease, infarction, myocarditis, cardiomyopathies, valvular disease. 10. Neuropathology. 11. Hematopathology. 12. Toxins/environmental injury. 13. Genetic Diseases.
CMM5315
Cellular And Molecular Basis Of Cardiovascular Function/Dysfunction (3cr.)
Mechanism of failing heart and cardiovascular system, its associated functions and associated conditions. Therapies for restoring function. Topics include: regulation of heart development, cell signaling, cellular and molecular mechanisms of atherosclerosis and heart disease, hormonal regulation, hypertension, bioenergetics, cardiovascular genomics and genetics, cell therapy, and regenerative medicine.
CMM5105
Introduction To Cancer Bilogy (3cr.)
An introduction to the biology of cancer. Major topics in cancer biology include the following: tumor suppression/oncogenes; apoptosis in cancer; cell immortalization and senescence; genomic instability; multistep tumorigenesis/inflammation in cancer; biology of angiogenesis; rational therapies.
CMM8105
Advanced Topocs In Cancer Biology (3cr.)
Advanced study of recent developments in the field of cancer biology with emphasis on cellular and molecular aspects. Specific topics to be covered include: angiogenesis, apoptosis, cancer genetics, cell signaling, genetic instability, oncogenes and tumour suppressors.
BCH8107
Advanced Topics In Structure And Function Of Plasma Liporoteins (3cr.)
Recent advances in our knowledge of the plasma lipoproteins with a special emphasis on their role in the etiology of atherosclerosis. The subject will be introduced by an overview of the general structural properties of lipoproteins which will be followed by detailed discussion of the structure, metabolism and genetics of the apolipoproteins, the proteins and enzymes that modify lipoproteins and cell surface lipoprotein receptors. Other topics will include cholesterol homeostasis, plasma cholesterol transport and disorders of lipoprotein metabolism.