Dr. Ajoy Basak

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Dr. Ajoy Basak
Adjunct Professor, Pathology & Laboratory Medicine Affiliate Investigator, Ottawa Hospital Research Institute, U Ottawa Dept. U Ottawa, ON, Canada and Adjunct Professor, Pathology & Laboratory Medicine Dept. U Ottawa, ON, Canada

MSc, PhD, FIC

Office: 613-878-7043
Work E-mail: abasa2@uottawa.ca
Personal E-mail: Ajoybasak1@gmail.com

Dr. Ajoy Basak

Biography

Courses Taught

HSS2305B (Molecular mechanism of diseases); HSS3305A (Pathophysiology of health problems); HSS5903 (Seminar); BCH3125 (Protein Chemistry course); BCH4040 (Honors Research Project)

Research Publications

2018

  • A. Basak and S. Basak. Molecular Tags for Proteins: A Review on Structures, Functions and Biological Applications. Current Proteomics, 15(5):401-427, 2018
  • B. Kadio, S.H. Yaya, A. Basak, J. Gomes, K. Dje, C. Mesenge. An integrative model of cancer disparities based on the calcium molecular theory of carcinogenesis. Cancer Epidemiology, Biomarkers & Prevention (CEBP) [1055-9965], 27 (7), 74, 2018.

2019

  • J. Gomes, F. Au, A. Basak, S. Cakmak, R. Vincent and P. Kumarathasan. Maternal blood biomarkers and adverse pregnancy outcomes: a systematic review and meta-analysis. Crit Rev Toxicol. 11:1-18, 2019, doi: 10.1080/10408444.2019.1629873.
  • B. Kadio, D.J.E. Koffi, C. Amed, N. Nezi, C. Amon, J. Gomes, A. Basak and S. Yaya. Development and validation of a food frequency questionnaire for assessing dietary calcium intake in elderly Sub-Sahara-African men-The African Prostate Cancer Study. J. of Nutrition and Metabolism, Submitted, Under revision, Aug 27, 2019, #6825981.

 

2020

  • A. Hicks, J. Minor, M. Chetta, B. Kadio, H.S. Yaya, A. Basak, A. Coulibaly and Nezi E5. Rheumatic Diseases in Aged Homeless in US and Canada. Archives of Rheumatology & Arthritis Research, 1(2), 1-7, 2020.

2021

  • A. Basak and S. Basak. Unique nCoV-2019 (COVID 19) spike glycoprotein processing by host protease: Analysis and Implication on infection. Current Proteomics, 18(2), 98-105, 2021. DOI:10.2174/1570164617999200612115218.
  • A. Basak, J. Vaijanathappa and S. Basak. Prevention of the Severity of COVID-19 Infection Using Lipid-lowering Natural Products to Target hPCSK9. Coronavirus, 2, 1-10, 2021. DOI: 10.2174/2666796702666210329141042
  • A. Basak and S. Basak.  Protein self-assembly and aggregation in Health and Disease, Current Proteomics, 18, 1-16, 2021, DOI: 10.2174/1570164618666210223160742.
  • A. Basak. K. Lynn Yelle Labre, J. Gomes, and A. Mohammad. Impact of Tobacco Smoking on Human Salivary Proteome and Proteolytome, Proceedings International, 2, 2021, In press.
  • B. Kadio; K. Djè; C. Amed; N. Konan Nezi; C. Adjo Amon; J. Gomes; A. Basak; S. H. Yaya. Calcium intake and prostate cancer risk, a large-scale prospective cohort of elderly Sub-Sahara-African men: Study design and pilot research - The African Prostate Cancer Study. Pilot and Feasibility Studies. PAFS-D-19-00167. 2021, In press.

BOOK CHAPTER

  • A. Basak and S. Basak. Implementing Green Chemistry for Synthesis of Cholesterol Lowering Statin Drugs. Invited contribution in the book "Sustainable and Green Approaches in Medicinal Chemistry". (Ed: Dr. Bimal Banik), Elsevier Inc., Pt III, Chapter16, p577-601, 2020.

Fields of Interest

  • Mammalian Subtilase Superfamily The PCSKs (Proprotein Convertase Subtilisin Kexins) - Role in health and diseases
  • Cholesterol regulation
  • Cardiovascular Disease and PCSK9
  • Proteolytic enzymes and Designing inhibitors
  • Proteomics study
  • Mass spectrometry
  • Peptide synthesis
  • Protein secondary structure analysis
  • Circular Dichroism
  • FT-IR
  • Viral and Bacterial infections
  • Malaria diagnosis
  • Pro-protein processing and maturation
  • Tumorgenesis
  • Dementia and Protein aggregation
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