Research teams from the Faculty of Medicine and affiliated Research Institutes awarded more than $12,2M to support cutting-edge research through the Spring 2021 CIHR Project Grant competition!

Posted on Thursday, July 29, 2021

The Spring 2021 Project Grant competition of the Canadian Institutes of Health Research (CIHR) has granted more than $12,2M to eighteen research teams from the Faculty of Medicine and affiliated Research Institutes to support their innovative research projects.

The Project Grant Program supports researchers in all areas of health and aims to capture ideas with the greatest potential to advance health-related fundamental or applied knowledge, health research, health care, health systems, and/or health outcomes.


  • Michele Ardolino (Ottawa Hospital Research Institute (OHRI)/Biochemistry, Microbiology and Immunology): “When the Killers become Thieves: NK cells are suppressed by trogocytosed PD-1”


  • Paul Beaule ( OHRI/Surgery): “ Periacetabular Osteotomy with or without arthroscopic management in patients with hip dysplasia: A multicenter randomized controlled trial “


  • David Birnie (University of Ottawa Heart Institute (UOHI)/Medicine): “Cardiac Sarcoidosis Multi-Center Randomized Controlled Trial (CHASM CS- RCT)”


  • Jason Brophy (Children’s Hospital of Eastern Ontario Research Institute (CHEO-RI)/Pediatrics): “Congenital CMV ANd HEARing in Ontario: Optimizing Screening to Improve Child Health Outcomes (CAN HEAR ONTARIO)”


  • Vanessa D'Costa (Biochemistry, Microbiology and Immunology): “Acinetobacter baumannii: Mechanisms of Pathogenesis and Evasion of Host Cellular Immunity”


  • Stephen Ferguson (Cellular and Molecular Medicine): “Investigation of GPCR Pharmacology in Alzheimer's Diseases”


  • Brian Hutton (OHRI/School of Epidemiology and Public Health): “Models for Primary Medical Care, Nursing Care and Personal Care in Long-Term Care Homes: Systematic Reviews to Inform Change in Canada”


  • Robert Jankov (CHEO-RI/Pediatrics): “Ceramides as a therapeutic target in experimental bronchopulmonary dysplasia”


  • Seung-Hwan Lee (Biochemistry, Microbiology and Immunology): “Hypoxic-specific activation of natural killer cells: Being resilient in the tumor microenvironment”


  • Patricia Longmuir (CHEO-RI/Pediatrics): “Preventing Sedentary Lifestyles among Children Born with Congenital Heart Defects: A Feasibility Study of Physical Activity after Surgical or Catheterization Intervention”


  • Katharine O'Hearn (CHEO-RI): “Patient and Family Perspectives on Operationalized Assent in Canadian Pediatric Intensive Care Research: A Survey and Interview Study”


  • Clare Liddy (Bruyere Research Institute/Family Medicine): “Improving access to specialized care for patients with frailty through eConsult”


  • Robin Parks (OHRI/): “Extracellular vesicles as a biomarker and therapeutic for Spinal Muscular Atrophy”


  • Monique Potvin Kent (School of Epidemiology and Public Health): “The Digital Marketing of Unhealthy Food and Beverages to Children and Youth: Examining Gendered Differences in Exposure and Impact”


  • Jennifer Reed (UOHI/School of Epidemiology and Public Health): “A multi-site population health study evaluating the physical activity levels of patients with atrial fibrillation (CANSURVEY-AF)”


  • Ryan Russell (Cellular and Molecular Medicine): “Identification of VHL-dependent dysfunction of the retinoblastoma protein in renal cancer”


  • Julie St-Pierre (Biochemistry, Microbiology and Immunology): “Genetic models of the metabolic regulator PGC-1alpha in breast cancer”


  • William Stanford (OHRI/Cellular and Molecular Medicine): “ Regulation of the epigenome by replication stress in vascular disease and aging”


  • Peter Tugwell (Bruyere Research Insitute/Medicine): “Stakeholder engagement in health care systematic reviews”


  • Tzu-Fei Wang (OHRI/Medicine): “Reducing bleeding with DOACs in breast cancer patients: The STOP-Bleed Cancer Study”


  • George Wells (UOHI/Medicine): “Living systematic reviews of pharmacological treatments for Rheumatoid Arthritis”
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