Cell and Cancer Biology

Molecular basis of the cell and cancer biology

Cells are the fundamental units of life and all aspects of cellular behavior are tightly regulated within our bodies. Indeed, defective control of cell division, cell differentiation and cell behavior underlies the development of diseases such as cancer. Researchers study how cancer cells repair their DNA, regulate their genes, differentiate, migrate, and recruit blood vessels in order to uncover both the mechanisms of disease as well as identify new therapeutic targets. This work is often conducted collaboratively, with clinicians providing insights from patients and basic scientists studying the molecular and cellular basis of the disease.  At the same time, they also investigate existing therapeutics to identify factors that may predict which patients are most likely to benefit and to determine how their application might be improved.

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